The ADRC Biomarker Lab is a core facility that provides lab equipment, analyzers, expertise, and support for studying neurological and other fluid biomarkers. These resources are available to collaborators in the UW system and non-UW clients. The ADRC Biomarker Lab supports the investigation of proteinopathies related to Alzheimer’s Disease and other dementias through biofluid analysis for cohorts such as WRAP, ADRC, and other linked studies. Although our expertise focuses on AD biomarkers, we are also able to analyze samples for other applications through fee-for-service. Contact us for more information about our capabilities and how we can assist in your study.
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Alamar Argo HT
- Fully automated platform with integrated qPCR detection for singleplex assays
- Utilizes NUcleic acid Linked Immuno-Sandwich Assay (NULISA) technology to achieve lower detection limits and higher selectivity compared to traditional ELISA analyses.
- High multiplexing abilities (>100 biomarkers) when combined with Next Gen Sequencing (NGS) using our in-house NextSeq 1000
- Samples analyzed in 96-well plates
Fujirebio Lumipulse G1200
- Clinical-grade, fully automated chemiluminescent enzyme immunoassay (CLEIA) instrument
- Ideal for rapid screening with 30-min result time per sample
- Ability to run multiple assays on one sample
- Samples analyzed in aliquot tubes
Quanterix HD-X
- Fully automated bead-based ELISA instrument
- High sensitivity and dynamic range due to Single Molecule Array (SIMOA) technology
- Ability to develop custom-assays
- Samples analyzed in 96-well plates